Job title
Senior Researcher, Nutritional Function Laboratory, Food Function Division
Resume
April 1996: Researcher, National Institute of Food ResearchDecember 2000: Completed a doctorate in nutritional scienceSeptember 2002-September 2004: Postdoctoral Fellow, Beltsville Human Nutrition Research Center, Department of Agriculture, USAApril 2006: Current position
Specialization
Nutritional Chemistry, Food Function Science
Research themes
1) Elucidation of the lipid metabolism regulation function of food ingredients in fat tissue and the liver
2) Analysis of the effects of phytochemicals on metabolic function using DNA microarray
Research achievements
(Original papers, etc.)
- Y. Takahashi, T. Ide, Effects of soy protein and isoflavone on hepatic fatty acid synthesis and oxidation and mRNA expression of uncoupling proteins and peroxisome proliferator-activated receptor gamma in adipose tissues of rats, J. Nutr. Biochem. 19, 682-693 (2008)
- Y. Takahashi, T. Ide, Alteration by dietary soy isoflavone of SREBP-1-dependent genes in the liver of rats fed a high saturated-fat diet, Rept. Natl. Food Res. Inst. 71, 7-13 (2007)
- Y. Takahashi, S.N. Perkins, S.D. Hursting, T.T.Y. Wang, 17beta-estradiol differentially regulates androgen-responsive genes through estrogen receptor-beta- and extracellular-signal regulated kinase-dependent pathways in LNCaP human prostate cancer cells, Mol. Carcinog. 46, 117-129 (2007)
- Y. Takahashi, J.A. Lavigne, S.D. Hursting, G.V.R. Chandramouli, S.N. Perkins, Y.S. Kim, T.T.Y. Wang, Molecular signatures of soy-derived phytochemicals in androgen-responsive prostate cancer cells:a comparison study using DNA microarray. Mol. Carcinog. 45, 943-956 (2006)
- Y. Takahashi, S. D. Hursting, S. N. Perkins, T.-C. Wang, T. T. Y. Wang, Genistein affects androgen-responsive genes through both androgen- and estrogen-induced signaling pathways. Mol. Carcinog. 45, 18-25 (2006)
- Y. Takahashi, J.A. Lavigne, S.D. Hursting, G.V.R. Chandramouli, S.N. Perkins, B.J. Carrett and T.T.Y. Wang, Using DNA microarray analyses to elucidate the effects of genistein in androgen-responsive prostate cancer cells: Identification of novel targets. Mol. Carcinog. 41, 108-119 (2004)
- Y. Takahashi, M. Kushiro, T. Ide, Effect of dietary protein on adipose tissue gene expression in mice. Rept. Natl. Food Res. Inst. 68, 11-18 (2004)
(Publications)
- Yoko Takahashi: Lipid metabolism regulation mechanism of food ingredients in fat tissue and liver. "Food- its science and technology" 44, 73-91 (2006)
Society membership
- Japanese Society of Nutrition and Food Science
- Japan Society for Bioscience, Biotechnology, and Agrochemistry
