The porcine lysozyme gene was artificially synthesized and expressed in the silk gland. A large amount of recombinant porcine lysozyme (about 0.5 mg/cocoon) accumulated in the sericin layer of the silk thread. The physicochemical properties were the same as the natural type. The porcine lysozyme easily flowed from the silk thread and showed high antibiotic properties. The antibiotic properties of the porcine lysozyme were excellent compared with the human and egg white lysozymes.
(Research Team for Advanced Biologicals)
References:
- Tsuchiya Y. et al. (2009) JARQ, 43: 207-212
- Tsuchiya Y. et al. (2008) Patent 2008-187954
