National Institute of Animal Health (NIAH)

Topics in Animal Health Research 1995

11. cDNA cloning of bovine and porcine GM-CSF and recombinant GM-CSF production by the baculovirus expression system


cDNA of bovine and porcine GM-CSF which activate phagocytic and bactericidal cells, were cloned by RT-PCR, using bovine and porcine T cell RNA as temperates and produced efficiently by the baculovirus expression system. It is thus possible to conduct animal experiments with GM-CSF administration.
(Lab. of Bioenginieering Research, Biological Products Research Division)