National Institute of Animal Health (NIAH)

Topics in Animal Health Research 1995

25. Antibody response of sika deer (Cervus nippon) against 4 kinds of bovine vaccine viruses


Adult sika deer (Cervus nippon) were inoculated with bovine viral vaccines (Infectious Bovine Rhinotracheitis (IBR), Akabane Disease (AD), Bovine Viral Diarrhea-Mucosal Disease (BVD-MD) and Parainfluenza Type 3 (PI-3)) for examination of clinical signs and serological response. No respiratory or intestinal diseases were noted. Serologic response was monitored by the serum neutralization test for IBR, AD and BVD-MD, and hemagglutination inhibition test for PI-3. Except for IBR, antibodies for each virus were detected at only 2 weeks post-inoculation and in nearly all animals were persistently seropositive for more than 12 weeks. The IBR antibody could not always be detected by only one vaccination but after second vaccination it could not always be found for more than 10 weeks with low titers.
(First Lab., Tohoku Branch)