To elucidate the mechanism of anemia in Japanese bovine theileriosis, the appearance of phosphatidylserine on the cell surface in Theileria orientalis sergenti-infected erythrocytes was investigated by using FITC-conjugated annexin V. When erythrocytes were treated with a variety of oxidants, translocation of phosphatidylserine to the external cell surface was detected by flow cytometric analysis. Phosphatidylserine exposure of the erythrocyte surface was also observed at the onset of anemia from Theileria orientalis sergenti infection. (Lab. of Clinical Biochemistry, Hokkaido Research Station TEL +81-11-851-5226)
References:
- Shiono, H. et al.: 17th International Conference of the World Association for the Advancement of Veterinary Parasitology (1999)
- Yagi, Y. et al.: 26th World Veterinary Congress 1999 p.97 (1999)
