National Institute of Animal Health (NIAH)

Topics in Animal Health Research 2004

02. Development of highly specific and rapid detection ELISA for neutralizing antibody to foot-and-mouth disease virus, O/JPN/2000


Liquid phase competition ELISA, used for the detection of neutralizing antibodies to foot-and-mouth disease virus (FMDV), O/JPN/2000, was developed using the monoclonal antibody to FMDV, O/JPN/2000. The result correlated to this method and the virus neutralization test, and the rate of non-specific reaction of this method is less than that of the present liquid phase competition ELISA. Consequently it is possible to use this method for serological surveillance and for diagnosing infected animals that do not show symptoms.
(Epizootiology Section, Department of Exotic Disease TEL +81-42-321-1441)


Yoshida and Sakamoto (2001) Report of the second meeting on foot and mouse disease control in East Asia, OIE: 118-124.