食品研究部門

感覚機能解析ユニット

日下部 裕子 (くさかべ ゆうこ)
Yuko KUSAKABE

職名

食品健康機能研究領域 感覚機能解析ユニット ユニット長

専門分野

博士(農学)

食品機能学、分子生理学

研究業績

  • Kusakabe Y, Shindo Y, Kawai T, Takahashi Y, Kobori M, Inoue H, Saito I., Sex-Based Differences in Smgc Expression in the Submandibular Gland of C57BL/6 Mice., Pathobiology. 2016, 83(6), 287-294.
  • Nango E, Akiyama S, Maki-Yonekura S, Ashikawa Y, Kusakabe Y, Krayukhina E, Maruno T, Uchiyama S, Nuemket N, Yonekura K, Shimizu M, Atsumi N, Yasui N, Hikima T, Yamamoto M, Kobayashi Y, Yamashita A., Taste substance binding elicits conformational change of taste receptor T1r heterodimer extracellular domains., Sci Rep. 2016, 6, 25745. doi: 10.1038/srep25745.
  • Miura H, Kusakabe Y, Hashido K, Hino A, Ooki M, Harada S., The glossopharyngeal nerve controls epithelial expression of Sprr2a and Krt13 around taste buds in the circumvallate papilla., Neurosci Lett. 2014, 580, 147-52.
  • Sanematsu K, Kusakabe Y, Shigemura N, Hirokawa T, Nakamura S, Imoto T, Ninomiya Y., Molecular mechanisms for sweet-suppressing effect of gymnemic acids., J Biol Chem. 2014, 289(37), 25711-20.
  • Shimizu M, Goto M, Kawai T, Yamashita A, Kusakabe Y., Distinct human and mouse membrane trafficking systems for sweet taste receptors T1r2 and T1r3., PLoS One. 2014, 9(7), e100425. doi: 10.1371/journal.pone.0100425. eCollection 2014.
  • Ashikawa Y, Ihara M, Matsuura N, Fukunaga Y, Kusakabe Y, Yamashita A., GFP-based evaluation system of recombinant expression through the secretory pathway in insect cells and its application to the extracellular domains of class C GPCRs., Protein Sci. 2011, 20(10), 1720-34.
  • Shindo Y, Morishita K, Kotake E, Miura H, Carninci P, Kawai J, Hayashizaki Y, Hino A, Kanda T, Kusakabe Y., FXYD6, a Na,K-ATPase regulator, is expressed in type II taste cells., Biosci Biotechnol Biochem. 2011, 75(6), 1061-6.
  • Shindo Y, Kim MR, Miura H, Yuuki T, Kanda T, Hino A, Kusakabe Y. Lrmp/Jaw1 is expressed in sweet, bitter, and umami receptor-expressing cells., Chem Senses. 2010, 35(2), 171-7.
  • Shindo Y, Miura H, Carninci P, Kawai J, Hayashizaki Y, Ninomiya Y, Hino A, Kanda T, Kusakabe Y., G alpha14 is a candidate mediator of sweet/umami signal transduction in the posterior region of the mouse tongue., Biochem Biophys Res Commun. 2008, 376(3), 504-8.
  • Nakayama A, Miura H, Shindo Y, Kusakabe Y, Tomonari H, Harada S., Expression of the basal cell markers of taste buds in the anterior tongue and soft palate of the mouse embryo., J Comp Neurol. 2008, 509(2), 211-24.
  • Miura H, Nakayama A, Shindo Y, Kusakabe Y, Tomonari H, Harada S., Expression of gustducin overlaps with that of type III IP3 receptor in taste buds of the rat soft palate., Chem Senses. 2007, 32(7), 689-96.